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WebIn well-differentiated tumors, the lesional cells form intercellular bridges, have abundant eosinophilic cytoplasm, and may have individual cell keratinization. 30 They can form keratin pearls and have variable architectural patterns. 7 Moderately or poorly differentiated squamous cell carcinomas have lost these morphologic indications of their squamous … WebPoorly differentiated – These cancers look very abnormal. When the cells from a poorly differentiated tumour travel to a lymph node or other part of the body, additional tests such as immunohistochemistry may be required to determine the type of tumour and where it … WebJan 12, 2024 · The expression of HNF6 and differentiation-related markers in poorly differentiated hepatocellular carcinoma cells was lower than that in well differentiated hepatocellular carcinoma cells . HNF6 can up-regulate the expression of differentiation-related markers and inhibit the migration and invasion of hepatocellular carcinoma cells, … how old is 40kg child