Cisplatin and hypokalemia
WebSep 20, 2024 · The most common adverse reactions in the two trials (≥25% with difference between arms of >5% compared to cisplatin alone) were vomiting, nausea, decreased hemoglobin, hypernatremia, and... WebDigitalis therapy may exaggerate metabolic effects of hypokalemia, especially myocardial effects. All patients receiving LASIX therapy should be observed for these signs or symptoms of fluid or ... There is a risk of ototoxic effects if cisplatin and LASIX are given concomitantly. In addition, nephrotoxicity of nephrotoxic drugs such as ...
Cisplatin and hypokalemia
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WebMar 24, 2024 · Case 1: A case of hyponatremia following cisplatin chemotherapy A 64 year-old man with small cell lung cancer was treated with cisplatin chemotherapy with etoposide and concurrent chest radiotherapy. Serum sodium was 137 mmol/L prior to initiation of chemotherapy. WebNov 24, 2024 · fast, slow, or irregular heartbeat. headache (sudden and severe) hives, itching, skin rash. inability to speak. nervousness. noisy breathing. pain or discomfort in the arms, jaw, back, or neck. pounding in the ears. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue.
WebMay 18, 2024 · Impaired kidney function is a relatively common complication of amphotericin B, as are other kidney manifestations, including urinary potassium wasting and hypokalemia, urinary magnesium wasting and hypomagnesemia, metabolic acidosis due to type 1 (or distal) renal tubular acidosis (RTA), and polyuria due to nephrogenic diabetes … WebApr 15, 2024 · Eventually, nephrotoxicity complicated by hypomagnesaemia was confirmed, and cisplatin-induced nephrotoxicity led to the final diagnosis of a familial form of …
WebHypomagnesemia generally resolves with cessation of therapy. Cisplatin can cause increased magnesium losses by the kidneys as well as generalized decrease in kidney function. Magnesium loses can be severe and persist despite discontinuation of cisplatin. WebMedications that cause RTA include Cisplatin and Amphotericin B. You may have hypokalemia from a loss of body fluids due to excessive vomiting, diarrhea, or …
WebJan 12, 2024 · Hypomagnesemia is often associated with hypokalemia (due to urinary potassium wasting) and hypocalcemia (due both to lower parathyroid hormone secretion and end-organ resistance to its effect). (See "Hypomagnesemia: Clinical manifestations of magnesium depletion" .) The major causes of hypomagnesemia will be reviewed in this …
WebCisplatin-based combination chemotherapy is recommended as first-line systemic therapy for patients with metastatic BC based on a relative risk of nearly 50%. 44 The … granulomatous prostatitis pathology outlinesWebis a major concern when prescribing cisplatin. Renal dysfunction due to cisplatin may manifest as renal insufficiency, hypokalemia and hypomagnesemia. The risk for these adverse effects is related to the dose and interval of cisplatin and may be minimized by adequate hydration. Geriatric patients may also be at increased risk. chippenham window cleanersWebApr 10, 2024 · Med-Surg Nursing. Hypocalcemia is when there are low levels of calcium in the blood. Calcium is an electrolyte that plays a vital role in many bodily functions, including muscle contraction, nerve transmission, and bone formation. Various factors, including nutritional deficiencies, medications, and underlying medical conditions, can all lead ... chippen holdingsWebKey Points. When evaluating hypokalemia, use the history to explore possible losses (renal vs. GI), shifts (pH, insulin, etc.), and intake. Get a full medication history. Then use the … granulomatous pathologyWebJul 24, 2024 · Cisplatin, a chemotherapeutic drug, can also cause hypocalcemia through hypomagnesemia. Foscarnet can cause hypocalcemia by forming complexes with ionized calcium, thereby … chippenham wound center richmond vaWebThe Radiation Therapy Oncology Group launched a phase III trial to test the hypothesis that adding cetuximab to the radiation-cisplatin platform improves progression-free survival (PFS).Patients and methodsEligible patients with stage III or IV HNC were randomly assigned to receive radiation and cisplatin without (arm A) or with (arm B) cetuximab. chippenham wickesWebFirst-line multiagent chemotherapy comprises doxorubicin, cisplatin, and high-dose methotrexate (MAP regimen) . ... Regarding toxicity, rash and hypokalemia was the most common grade 3 adverse event, and one death from end organ failure was reported that was possibly related to the drug. granulomatous pulmonary disease icd 10