Cenpf 肿瘤

Author: ilbd

August undefined, 2024

WebThe effect of silencing CENPF on cell viability, migration, and epithelial-mesenchymal transition (EMT) were detected using CCK-8, transwell, and western blot, respectively. RT-qPCR and western blot were performed to confirm the silencing of CENPF and the relationship between STAT5A and CENPF, while tumorigenesis was tested using the … Web利用世界上最大的癌症研究超级计算机，解析结果鉴别出了foxm1和cenpf是小鼠和人类侵袭性前列腺癌的一个成对协同作用驱动子，这些调控因子共同控制了与两个物种中最显著 …

肿瘤新热点：HMMR+风险预后模型，轻松发6+ - 知乎

WebJan 10, 2024 · CENPF and ERβ2/5 were related with T stage and poor prognosis (P<0.05). CENPF knockout significantly inhibited LUAD cell growth, the tumor growth of mice and the expression of ERβ2/5 (P<0.05). The protein expression of CENPF and ERβ2/5 in the CENPF-Knockdown+Fulvestrant group was lower than CENPF- Negative Control … WebJan 31, 2024 · CENPF (centromere protein) is a key regulator of cell cycle progression, but its role in TNBC chemotherapy resistance remains unclear. tim ica

CENPF knockdown inhibits adriamycin chemoresistance in …

WebCENP-F (mitosin) 是其表达和定位至染色质以细胞周期依赖性方式受调节的动粒相关蛋白，它在 G2/M 期中表达最高 (1, 2)。. CENP-F 是其他动粒相关蛋白（包括 CENP-E）适 … Web其中，cenpf在肿瘤样本和转移样本中高表达。km分析，roc曲线，单因素和多因素分析表明cenpf是独立预后因子。cibersort分析表明，转移样本中cd4+ 记忆激活t细胞浸润水平较高。ssgsea分析表明cenpf与活化cd4+ t细胞 … Web摘要目的探讨着丝粒蛋白f(cenpf)基因在肝细胞癌中的表达情况及其与患者临床特征、预后的关系,通过基因集富集分析(gsea)寻找cenpf基因在肝细胞癌中的相关调控通路。方法从癌症基因组图谱(tcga)数据库中获取369例肝细胞癌组织样本和50例癌旁组织样本cenpf基因表达数据,以及其中240例病例的临床资料和 ... bau istanbul majors

Knockdown of CENPF inhibits the progression of lung ... - PubMed

CENPF knockdown inhibits adriamycin chemoresistance in triple …

WebFeb 27, 2024 · 600236 - CENTROMERIC PROTEIN F; CENPF - MITOSIN - CENPF Liao et al. (1995) reported the expression and localization patterns of CENPF at different stages of the HeLa cell cycle. CENPF is a protein of the nuclear matrix that gradually accumulates during the cell cycle until it reaches peak levels in G2- and M-phase cells and is rapidly … WebFeb 5, 2024 · Background Adrenocortical carcinoma (ACC) is an aggressive and rare malignant tumor and is prone to local invasion and metastasis. And, overexpressed Centromere Protein F (CENPF) is closely related to the oncogenesis of various neoplasms, including ACC. However, the prognosis and exact biological function of CENPF in ACC … baujagd youtubehttp://www.lcgdbzz.org/cn/article/doi/10.3969/j.issn.1001-5256.2024.07.022 baujahr a45

"WebOct 11, 2024 · Background Centromere Protein F (CENPF) associates with the centromere–kinetochore complex and influences cell proliferation and metastasis in several cancers. The role of CENPF in breast cancer (BC) bone metastasis remains unclear. Methods Using the ONCOMINE database, we compared the expression of CENPF in … " - Cenpf 肿瘤

Cenpf 肿瘤

Cancer Science: Vol 113, No 4 - Wiley Online Library

http://qikan.cqvip.com/Qikan/Article/Detail?id=7105190800 Web摘要: 目的探讨着丝粒蛋白F（CENPF）基因在肝细胞癌（HCC）患者组织中的表达情况及与临床特征和预后的相关性。. 方法利用在线工具Oncomine分析CENPF在HCC与正常肝组 …

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WebOct 6, 2024 · TOP2A and CENPF are a synergistic pair of MRs that are overexpressed and activated in CC. Their high expression is correlated with some prognosis features (e.g. metastasis) and molecular features (e.g. somatic mutations) and distinctly high in CC vs. many other cancer types. They may be good biomark … Web1.用于治疗受试者中表达cxcl12的癌症的方法中的用途的替比法尼，其中所述癌症是外周t细胞淋巴瘤(ptcl)或急性髓性白血病(aml)。 2.如权利要求1所述用途的替比法尼，其中所述ptcl为复发性或难治性ptcl；或其中所述ptcl是血管免疫母细胞性t细胞淋巴瘤(aitl)。 3.如权利要求2所述用途的替比法尼，其中所述 ...

WebUpregulated CENPF might lead to premature depletion of CD4+ memory T cells and immunosuppression. Nomogram indicated CENPF clinical predictive value for 1-, 3-, 5-, and 7-year melanoma overall survival. Therefore, CENPF plays a vital role in the progression and metastasis of melanoma and can be an effective therapeutic target. WebCENPF is part of the nuclear matrix during the G2 phase of the cell cycle (the phase of rapid protein synthesis in preparation for mitosis ). In late G2, the protein forms part of the kinetochore, a disc-shaped protein complex that allows the centromere of two sister chromatids to attach to microtubules (forming the spindle apparatus) in order ...

WebJan 31, 2024 · CENPF (centromere protein) is a key regulator of cell cycle progression, but its role in TNBC chemotherapy resistance remains unclear. Here, we found that CENPF, which is highly expressed in TNBC ... WebCycling N/A Neural G2M & S-Phase (66) MKI67, CENPF, TOP2A No locational preference Decreases in time in colon and overall Glial S100B, SOX10, PLP1 Lymphoid associated glial (67) FGL2, GFRA3, RXRG Increased in colon (**) Increases over time in colon and overall l B Intraganglionic glial (68) ENTPD2, SPRY1, SOX6

Web摘要 (Abstract)：. 目的探讨微小RNA-383-5p (miR-383-5p)是否可靶向T细胞分化蛋白2 (MAL2)调控三阴性乳腺癌（TNBC）肿瘤细胞侵袭及转移。. 方法 RT-qPCR技术检测TNBC细胞系（MDA-MB-468、MDA-MB-453、BT-549）和人永生化乳腺上皮细胞系（MCF-10A）中miR-383-5p表达水平；MDA-MB-453细胞 ...

WebJun 6, 2024 · Sun JB, Huang JZ, Lan J, et al. Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer. Cancer Cell Int. 2024; 19 (1):264. doi: 10.1186/s12935-019-0986-8. [ PMC free article ] [ PubMed ] [ CrossRef ] [ Google Scholar ] bau it meaningWebFeb 5, 2024 · The result points out that CENPF is significantly overexpressed in ACC patients. The overexpressed CENPF predicts a poor prognosis of ACC and might augment the progress of ACC. Thus, CENPF and related genes might serve as a novel prognostic biomarker or latent therapeutic target for ACC patients. bauixWebCENPF was immunoprecipitated from 1mg of HeLa (Human epithelial cell line from cervix adenocarcinoma) whole cell lysate with ab264215 at 3 µg/mg lysate. Western blot was … timica jacksonWeb图1 例3：肿瘤细胞弥漫分布图2 例3：肿瘤细胞大且多形，细胞核大而不规则，胞质丰富、嗜酸性，细胞边界清楚图3 例2：肿瘤细胞弥漫分布，其间可见反应性淋巴细胞图4 例2：肿瘤细胞CD30细胞质及高尔基体呈弥漫强阳性，EnVision法图5 例2：肿瘤细胞ALK呈细胞核 ... tim iceWebMay 1, 2024 · CENPF may be a key gene in regulation of the therapeutic effects of acupuncture in rheumatoid arthritis. Rheumatoid arthritis is a globally common autoimmune inflammatory disease found especially in China. Acupuncture (AP), a traditional Chinese medicine (TCM) treatment method, is commonly used for … bau itemWebApr 8, 2024 · This technique helps to prevent the influence of melanin pigmentation. Centromere protein F, related to CD4+ memory-activated T cell infiltration, is a vital indicator of advanced cutaneous melanoma and is associated with SKCM metastasis. CENPF may be a novel prognostic and immunotherapeutic target. Abstract. bau jahe artinyaWeb此外，tcga数据库中54例luad患者的肿瘤组织和配对的相邻非肿瘤组织数据(图1d)，以及包含111例癌症患者和111个相邻非肿瘤组织的cptac队列数据(图1e)也验证了该结果。 ... (top2a、pttg1、dlgap5、aspm、cep55、cenpf、ncapg、bub1、pbk、cdk1)，并构建了相应的ppi网络(p-value = 8.03e ... baujahr a1